STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1996Amino acid biosynthesis; Glutamate family; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (415 aa)    
Predicted Functional Partners:
PAE3227
Glutamate synthase small subunit gltD; Amino acid biosynthesis; Glutamate family.
  
 0.964
PAE1651
Isocitrate dehydrogenase; Energy metabolism; TCA cycle.
   
 0.951
PAE2251
Aspartate aminotransferase (aspC), conjectural; Amino acid biosynthesis; Aspartate family.
  
 
 0.926
PAE2556
Glutamine synthetase; Amino acid biosynthesis; Glutamate family; Belongs to the glutamine synthetase family.
  
 
 0.925
PAE3442
Glutamine synthetase; Amino acid biosynthesis; Glutamate family; Belongs to the glutamine synthetase family.
  
 
 0.925
PAE1964
Aspartate aminotransferase (aspC), conjectural; Amino acid biosynthesis; Aspartate family.
  
 
 0.923
PAE2577
Ferredoxin-nitrite reductase; Energy metabolism; Electron transport.
     
 0.919
PAE1552
Carbamate kinase; Energy metabolism; Amino acids and amines; Belongs to the carbamate kinase family.
     
 0.916
purQ
Phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...]
    
  0.909
PAE3438
Amino acid biosynthesis; Glutamate family; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 
0.901
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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