Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE2004Serine/threonine specific protein phosphatase; Regulatory functions; General. (279 aa)    
Predicted Functional Partners:
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
 
 
 0.957
PAE3333
Conserved hypothetical protein.
  
 0.954
PAE2936
Conserved hypothetical protein.
  
 0.919
PAE1693
TBP-interacting protein TIP49; Transcription; Transcription factors.
  
 
 0.891
PAE3196
Hypothetical protein.
   
 0.884
PAE0815
Serine/threonine protein kinase, putative; Regulatory functions; General.
 
 
 0.883
PAE3309
mRNA 3'-end processing factor, conjectural; Transcription; RNA processing.
   
 0.877
PAE3418
Conserved hypothetical protein.
   
 0.877
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
  0.851
PAE0692
Hypothetical protein with partial (eukaryotic) protein kinase domain; Unclassified.
   
 0.849
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.