Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE2022Conserved (helix-turn-helix protein, copG family); Regulatory functions; General. (122 aa)    
Predicted Functional Partners:
PAE2024
Conserved hypothetical protein.
       0.798
PAE2025
xaa-Pro dipeptidase, putative; Protein fate; Degradation of proteins, peptides, and glycopeptides.
       0.798
PAE1246
Manganese ABC transporter ATP-binding protein; Transport and binding proteins; Cations.
     
 0.713
PAE1247
Transport and binding proteins; Cations.
     
 0.683
PAE0564
Conserved hypothetical protein.
       0.652
PAE2021
Conserved hypothetical protein.
       0.588
PAE0636
Conserved hypothetical protein.
       0.563
PAE1185
Galactokinase; Energy metabolism; Sugars.
   
    0.409
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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