Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE2050Conserved hypothetical protein. (285 aa)    
Predicted Functional Partners:
PAE1653
Conserved hypothetical protein.
 
     0.726
PAE1638
Conserved hypothetical protein.
  
     0.640
PAE1627
Hypothetical protein.
  
     0.588
PAE3406
Conserved hypothetical protein.
 
     0.586
PAE0707
Conserved hypothetical protein.
  
     0.558
gap
Glyceraldehyde-3-phosphate dehydrogenase; Energy metabolism; Glycolysis/gluconeogenesis.
  
     0.546
PAE2255
Conserved hypothetical protein.
  
     0.538
PAE3407
Conserved hypothetical protein.
 
     0.516
PAE2048
P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome.
 
     0.510
rnz
Conserved hypothetical protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
      
 0.490
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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