Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE2053Pleiotropic regulatory protein, conjectural; Regulatory functions; General; Belongs to the DegT/DnrJ/EryC1 family. (404 aa)    
Predicted Functional Partners:
PAE1472
Acetyl/acyl transferase related protein; Fatty acid and phospholipid metabolism; Biosynthesis.
  
 0.926
PAE3281
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase, conjectural; Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
  
 0.924
PAE0870
Conserved NAD/P oxidoreductase; Unclassified.
 
  
 0.910
PAE2054
Hypothetical protein.
       0.578
PAE1922
UDP-glucose 4-epimerase (galE-1); Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
  
 0.567
PAE0439
Dolichol-phosphate mannosyltransferase; Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
  
 0.553
PAE3488
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
  
  
 0.548
PAE1927
Transketolase (C terminal section); Energy metabolism; Pentose phosphate pathway.
  
    0.533
PAE0437
Glycosyltransferase (type 2); Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
  
 0.518
PAE1555
Dolichol-phosphate mannosyltransferase; Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
  
 0.518
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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