Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE2072Conserved protein with 2 CBS domains; Unclassified. (138 aa)    
Predicted Functional Partners:
queC
Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
       0.791
PAE2071
Phosphoribosyl transferase; Unclassified.
     
 0.719
PAE3333
Conserved hypothetical protein.
 
 0.691
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.659
rpl23
Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
  
   0.628
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
  
   0.627
rps2
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the universal ribosomal protein uS2 family.
  
   0.620
PAE2070
acyl-CoA dehydrogenase; Fatty acid and phospholipid metabolism; Degradation.
   
 
 0.610
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
 0.602
rpl44e
Ribosomal protein L44; Binds to the 23S rRNA.
  
 
   0.600
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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