STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE2075Nitrilase, conjectural; Unclassified. (258 aa)    
Predicted Functional Partners:
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
   
 
 0.813
PAE2260
Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family.
  
 0.590
PAE2077
Conserved hypothetical protein.
       0.533
PAE3227
Glutamate synthase small subunit gltD; Amino acid biosynthesis; Glutamate family.
 
 
 0.495
pstB
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
   
    0.487
PAE1799
4-aminobutyrate aminotransferase; Amino acid biosynthesis; Glutamate family; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.470
PAE1807
Hypothetical; Conserved within genome.
  
  
 0.470
PAE1996
Amino acid biosynthesis; Glutamate family; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 0.460
PAE3438
Amino acid biosynthesis; Glutamate family; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 0.460
PAE3645
Aminotransferase, putative; Unclassified.
 
  
 0.453
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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