Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE2096Bacterial extracellular solute-binding proteins, family 3; Transport and binding proteins; Unknown substrate. (282 aa)    
Predicted Functional Partners:
PAE2000
Glutamine transport system permease protein, putative; Transport and binding proteins; Amino acids, peptides and amines.
 
 0.989
PAE2001
Glutamine transport ATP-binding; Transport and binding proteins; Amino acids, peptides and amines.
 
 
 0.883
rps14
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles.
  
  
 0.741
PAE2095
Hypothetical; Conserved within genome.
 
  
 0.665
rps8
Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
  
    0.603
argG
Argininosuccinate synthase (argG); Amino acid biosynthesis; Glutamate family; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.536
rpl18
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
    0.521
rpl32e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eL32 family.
       0.510
rpl19e
Ribosomal protein L19; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
       0.510
argH
Argininosuccinate lyase (argH); Amino acid biosynthesis; Glutamate family.
  
  
 0.445
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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