STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE2176CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA); Fatty acid and phospholipid metabolism; Biosynthesis; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (180 aa)    
Predicted Functional Partners:
PAE2177
Conserved hypothetical protein.
       0.861
PAE1761
Myo-inositol-1-phosphate synthase, conjectural; Fatty acid and phospholipid metabolism; Other.
 
   
 0.811
PAE1058
Glycerophosphoryl diester phosphodiesterase; Fatty acid and phospholipid metabolism; Degradation.
 
 
 0.794
trmY
Hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
       0.732
PAE0683
Cytidyltransferase; Unclassified.
  
  
 0.728
PAE0727
Molybdenum cofactor biosynthesis protein D/E; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
    0.725
PAE2972
Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
     
 0.716
PAE0875
Competence damage protein, conjectural; DNA metabolism; DNA replication, recombination, and repair; Belongs to the CinA family.
  
  
 0.705
PAE3257
DNA-(apurinic or apyrimidinic site) lyase (endonuclease IV); DNA metabolism; DNA replication, recombination, and repair.
     
 0.688
PAE1760
Conserved hypothetical protein.
       0.654
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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