STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmAProteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (243 aa)    
Predicted Functional Partners:
psmB2
Proteasome, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.912
PAE2024
Conserved hypothetical protein.
   
 0.911
psmB1
Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.909
rpl40e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.852
rpl15e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eL15 family.
 
  
 0.830
rpl4
Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
 
 
 0.800
PAE3171
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
 
 0.789
PAE0696
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
 
 0.788
eIF1A
Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
  
 
 0.785
PAE3273
Thermosome (chaperonin) beta subunit; Protein fate; Protein folding and stabilization; Belongs to the TCP-1 chaperonin family.
 
 
 0.782
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.