Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE2282Conserved hypothetical protein. (239 aa)    
Predicted Functional Partners:
PAE2284
Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
     
 0.687
PAE2449
Conserved hypothetical protein.
  
     0.585
PAE1263
Molybdopterin oxidoreductase, iron-sulfur binding subunit; Energy metabolism; Electron transport.
   
    0.561
PAE2661
Formate dehydrogenase beta subunit; Energy metabolism; Electron transport.
   
    0.561
PAE2837
Molybdopterin oxidoreductase, iron-sulfur binding subunit; Energy metabolism; Electron transport.
   
    0.561
PAE2860
Molybdopterin oxidoreductase, iron-sulfur binding subunit; Energy metabolism; Electron transport.
   
    0.561
PAE2210
Conserved hypothetical protein.
  
   
 0.552
PAE0653
Conserved hypothetical protein.
  
     0.509
PAE2019
Conserved hypothetical protein.
  
     0.473
PAE3336
Conserved hypothetical protein.
  
     0.467
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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