STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE2301ABC transporter ATP-binding component, degenerate; Transport and binding proteins; Unknown substrate. (361 aa)    
Predicted Functional Partners:
PAE0696
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
   
 0.761
PAE3171
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
   
 0.761
thiI
Thiamine biosynthesis protein (thiI), probable; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 
 0.760
sod
Superoxide dismutase (sod); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.668
infB
Translation initiation factor IF-2 (infB), putative; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
  
 
 0.662
PAE1683
Hypothetical protein.
 
 0.659
PAE0269
ABC-2 type transport system ATP-binding protein; Transport and binding proteins; Unknown substrate.
  
 0.620
PAE0315
ABC-2 type transport system ATP-binding protein; Transport and binding proteins; Unknown substrate.
  
 0.620
PAE1168
ABC transporter ATP-binding protein, putative; Transport and binding proteins; Anions.
  
 0.620
PAE1199
ABC transporter ATP-binding protein, putative; Transport and binding proteins; Unknown substrate.
  
 0.620
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.