node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PAE0716 | PAE0717 | PAE0716 | PAE0717 | Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle. | Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle. | 0.999 |
PAE0716 | PAE0718 | PAE0716 | PAE0718 | Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle. | Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle. | 0.999 |
PAE0716 | PAE0719 | PAE0716 | PAE0719 | Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle. | Succinate dehydrogenase subunit D (sdhD); Energy metabolism; TCA cycle. | 0.998 |
PAE0716 | PAE1651 | PAE0716 | PAE1651 | Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle. | Isocitrate dehydrogenase; Energy metabolism; TCA cycle. | 0.698 |
PAE0716 | PAE2648 | PAE0716 | PAE2648 | Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle. | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase); Energy metabolism; Glycolysis/gluconeogenesis. | 0.779 |
PAE0716 | sucC | PAE0716 | PAE2312 | Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle. | succinyl-CoA synthetase beta subunit (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.984 |
PAE0716 | sucD | PAE0716 | PAE2313 | Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle. | succinyl-CoA synthetase alpha subunit (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.983 |
PAE0717 | PAE0716 | PAE0717 | PAE0716 | Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle. | Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle. | 0.999 |
PAE0717 | PAE0718 | PAE0717 | PAE0718 | Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle. | Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle. | 0.999 |
PAE0717 | PAE0719 | PAE0717 | PAE0719 | Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle. | Succinate dehydrogenase subunit D (sdhD); Energy metabolism; TCA cycle. | 0.998 |
PAE0717 | PAE1651 | PAE0717 | PAE1651 | Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle. | Isocitrate dehydrogenase; Energy metabolism; TCA cycle. | 0.787 |
PAE0717 | PAE2648 | PAE0717 | PAE2648 | Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle. | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase); Energy metabolism; Glycolysis/gluconeogenesis. | 0.815 |
PAE0717 | sucC | PAE0717 | PAE2312 | Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle. | succinyl-CoA synthetase beta subunit (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.982 |
PAE0717 | sucD | PAE0717 | PAE2313 | Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle. | succinyl-CoA synthetase alpha subunit (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.984 |
PAE0718 | PAE0716 | PAE0718 | PAE0716 | Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle. | Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle. | 0.999 |
PAE0718 | PAE0717 | PAE0718 | PAE0717 | Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle. | Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle. | 0.999 |
PAE0718 | PAE0719 | PAE0718 | PAE0719 | Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle. | Succinate dehydrogenase subunit D (sdhD); Energy metabolism; TCA cycle. | 0.999 |
PAE0718 | PAE0939 | PAE0718 | PAE0939 | Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle. | 2-oxoacid ferredoxin oxidoreductase alpha subunit; Energy metabolism; Electron transport. | 0.414 |
PAE0718 | PAE1559 | PAE0718 | PAE1559 | Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle. | 2-oxoacid ferredoxin oxidoreductase alpha subunit; Energy metabolism; Electron transport. | 0.414 |
PAE0718 | PAE1651 | PAE0718 | PAE1651 | Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle. | Isocitrate dehydrogenase; Energy metabolism; TCA cycle. | 0.635 |