STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE2384Universal stress protein family; Cellular processes; Adaptations to atypical conditions. (137 aa)    
Predicted Functional Partners:
PAE2382
Conserved protein with 2 CBS domains; Unclassified.
  
    0.726
ogt
methylated-DNA--[protein]-cysteine S-methyltransferase (ogt); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
    0.591
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.507
PAE2364
Conserved protein with 4 CBS domains; Unclassified.
  
    0.465
PAE2421
Potassium transport peripheral protein, conjectural; Transport and binding proteins; Cations.
  
  
 0.456
prf1
Peptide chain release factor aRF subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
  
  
 0.442
PAE2117
Thermosome (chaperonin) alpha subunit; Protein fate; Protein folding and stabilization; Belongs to the TCP-1 chaperonin family.
  
 
 0.423
PAE3273
Thermosome (chaperonin) beta subunit; Protein fate; Protein folding and stabilization; Belongs to the TCP-1 chaperonin family.
  
 
 0.423
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.