STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secGHypothetical protein; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex (By similarity). (58 aa)    
Predicted Functional Partners:
PAE3435
Preprotein translocase secY subunit; Protein fate; Protein and peptide secretion and trafficking; Belongs to the SecY/SEC61-alpha family.
    
 
 0.561
PAE2388
Hypothetical protein.
       0.556
PAE3102
Hypothetical protein.
    
 
 0.500
tatC
Membrane protein (mttB family); Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
      
 0.493
PAE3100
Signal recognition particle protein (docking protein), probable; Protein fate; Protein and peptide secretion and trafficking.
      
 0.493
PAE0653
Conserved hypothetical protein.
       0.470
PAE1204
Pantothenate metabolism flavoprotein (dfp); DNA metabolism; DNA replication, recombination, and repair.
       0.470
rps6e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eS6 family.
       0.470
pdxT
Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.470
hisE
phosphoribosyl-ATP pyrophosphohydrolase; Amino acid biosynthesis; Histidine family.
       0.466
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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