Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE2445Ornithine cyclodeaminase (arcB); Energy metabolism; Amino acids and amines. (289 aa)    
Predicted Functional Partners:
PAE2446
DNA metabolism; DNA replication, recombination, and repair.
       0.792
PAE2447
Conserved hypothetical protein.
       0.792
PAE2442
Hypothetical protein.
       0.725
pth
Conserved hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
 
 
   0.649
PAE1051
Cysteine synthase; Amino acid biosynthesis; Serine family.
  
  
 0.569
PAE2251
Aspartate aminotransferase (aspC), conjectural; Amino acid biosynthesis; Aspartate family.
 
   
 0.549
PAE2260
Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family.
 
   
 0.542
PAE2310
Proline dehydrogenase; Amino acid biosynthesis; Serine family.
 
  
 0.479
PAE2439
Hypothetical; Conserved within genome.
       0.478
PAE1917
Pyrroline-5-carboxylate reductase; Amino acid biosynthesis; Glutamate family.
  
  
 0.470
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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