Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE2447Conserved hypothetical protein. (378 aa)    
Predicted Functional Partners:
PAE2446
DNA metabolism; DNA replication, recombination, and repair.
 
 
 
 0.996
PAE1611
Helicase, possible DNA repair rad25; DNA metabolism; DNA replication, recombination, and repair.
 
 
   0.920
PAE2445
Ornithine cyclodeaminase (arcB); Energy metabolism; Amino acids and amines.
       0.792
PAE2442
Hypothetical protein.
       0.721
PAE2439
Hypothetical; Conserved within genome.
       0.478
PAE0678
Conserved hypothetical protein.
  
     0.466
PAE2019
Conserved hypothetical protein.
  
     0.441
PAE2526
Conserved hypothetical protein.
  
     0.433
PAE0372
Conserved hypothetical protein; Belongs to the UPF0284 family.
  
     0.430
PAE1161
Hypothetical protein with conserved Forkhead-associated (FHA) domain; Unclassified.
  
     0.408
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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