Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAE2457Arsenite transport protein, conjectural; Transport and binding proteins; Anions. (421 aa)    
Predicted Functional Partners:
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.734
tdk
Thymidine kinase; Purines, pyrimidines, nucleosides, and nucleotides; Nucleotide and nucleoside interconversions.
  
    0.621
PAE2456
Conserved hypothetical protein.
       0.564
PAE2454
Conserved hypothetical protein.
     
 0.539
PAE2455
Protein synthesis; Ribosomal proteins: synthesis and modification.
       0.497
PAE2452
paREP13; Hypothetical; Conserved within genome.
       0.477
PAE1427
Arsenical pump-driving ATPase; Transport and binding proteins; Anions.
     
 0.476
tatC
Membrane protein (mttB family); Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
     
 0.469
PAE1884
Phosphate permease, conjectural; Transport and binding proteins; Anions.
  
  
 0.463
PAE3507
Conserved hypothetical protein.
 
     0.439
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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