Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE2475acyl-CoA dehydrogenase; Fatty acid and phospholipid metabolism; Degradation. (378 aa)    
Predicted Functional Partners:
PAE3587
Electron transfer flavoprotein alpha subunit (etfA); Energy metabolism; Electron transport.
 
 0.955
PAE0721
Electron transfer flavoprotein alpha subunit (etfA); Energy metabolism; Electron transport.
 
 0.915
PAE2479
enoyl-CoA hydratase; Fatty acid and phospholipid metabolism; Degradation.
 
 0.907
PAE1383
3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase; Fatty acid and phospholipid metabolism; Degradation.
 
 0.894
PAE3586
Electron transfer flavoprotein beta subunit (etfB); Energy metabolism; Electron transport.
 
 
 0.880
PAE1650
enoyl-CoA hydratase, probable; Fatty acid and phospholipid metabolism; Degradation.
  
 0.864
PAE0722
Electron transfer flavoprotein beta subunit (etfB); Energy metabolism; Electron transport.
  
 
 0.860
PAE2936
Conserved hypothetical protein.
  
 0.799
PAE2488
acetyl-CoA C-acyltransferase; Fatty acid and phospholipid metabolism; Degradation.
  
 0.787
PAE1377
acetyl-CoA C-acyltransferase; Fatty acid and phospholipid metabolism; Degradation.
  
 0.774
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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