Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE2486acetyl-CoA C-acyltransferase; Fatty acid and phospholipid metabolism; Degradation. (380 aa)    
Predicted Functional Partners:
PAE1383
3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase; Fatty acid and phospholipid metabolism; Degradation.
 
 0.994
PAE2185
3-oxoacyl-[acyl-carrier-protein] synthase; Fatty acid and phospholipid metabolism; Degradation; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 0.993
PAE2490
Conserved protein associated with acetyl-CoA C-acyltransferase; Fatty acid and phospholipid metabolism; Degradation.
 
 
 0.990
PAE2489
Conserved protein associated with acetyl-CoA C-acyltransferase; Fatty acid and phospholipid metabolism; Degradation.
 
 
 0.989
PAE2481
Acetyl-coenzyme A synthetase; Fatty acid and phospholipid metabolism; Degradation.
  
 
 0.972
PAE2488
acetyl-CoA C-acyltransferase; Fatty acid and phospholipid metabolism; Degradation.
 
  
 
0.972
PAE1689
Citrate synthase; Energy metabolism; TCA cycle.
  
 0.958
PAE3584
Citrate synthase part 1, authentic frameshift; Energy metabolism; TCA cycle.
  
 0.958
PAE3585
Citrate synthase part 2, authentic frameshift; Energy metabolism; TCA cycle.
  
 0.958
PAE2491
acyl-CoA dehydrogenase; Fatty acid and phospholipid metabolism; Degradation.
  
 0.945
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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