node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PAE2260 | PAE2480 | PAE2260 | PAE2480 | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | Aldehyde dehydrogenase; Unclassified. | 0.673 |
PAE2260 | argF | PAE2260 | PAE1985 | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.600 |
PAE2260 | argG | PAE2260 | PAE2884 | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | Argininosuccinate synthase (argG); Amino acid biosynthesis; Glutamate family; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.458 |
PAE2260 | argH | PAE2260 | PAE2887 | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | Argininosuccinate lyase (argH); Amino acid biosynthesis; Glutamate family. | 0.431 |
PAE2260 | carB | PAE2260 | PAE0947 | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | Carbamoyl-phosphate synthase large subunit; Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | 0.462 |
PAE2260 | guaA | PAE2260 | PAE3369 | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.509 |
PAE2260 | lysJ | PAE2260 | PAE2515 | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | Acetylornithine aminotransferase (argD); Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.829 |
PAE2260 | lysY | PAE2260 | PAE2881 | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | N-acetyl-gamma-glutamyl-phosphate reductase (argC); Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | 0.522 |
PAE2260 | lysZ | PAE2260 | PAE2882 | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | Acetylglutamate kinase (argB); Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. | 0.495 |
PAE2480 | PAE2260 | PAE2480 | PAE2260 | Aldehyde dehydrogenase; Unclassified. | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | 0.673 |
PAE2480 | argF | PAE2480 | PAE1985 | Aldehyde dehydrogenase; Unclassified. | Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.537 |
PAE2480 | guaA | PAE2480 | PAE3369 | Aldehyde dehydrogenase; Unclassified. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.609 |
PAE2480 | lysJ | PAE2480 | PAE2515 | Aldehyde dehydrogenase; Unclassified. | Acetylornithine aminotransferase (argD); Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.729 |
argF | PAE2260 | PAE1985 | PAE2260 | Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family. | 0.600 |
argF | PAE2480 | PAE1985 | PAE2480 | Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Aldehyde dehydrogenase; Unclassified. | 0.537 |
argF | argG | PAE1985 | PAE2884 | Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Argininosuccinate synthase (argG); Amino acid biosynthesis; Glutamate family; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.997 |
argF | argH | PAE1985 | PAE2887 | Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Argininosuccinate lyase (argH); Amino acid biosynthesis; Glutamate family. | 0.879 |
argF | carB | PAE1985 | PAE0947 | Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Carbamoyl-phosphate synthase large subunit; Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | 0.994 |
argF | lysJ | PAE1985 | PAE2515 | Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Acetylornithine aminotransferase (argD); Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.875 |
argF | lysK | PAE1985 | PAE2798 | Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Peptidase family M20/M25/M40; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. | 0.926 |