Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE2540Conserved hypothetical protein. (360 aa)    
Predicted Functional Partners:
PAE3468
Conserved hypothetical protein.
  
     0.607
PAE0656
Conserved hypothetical protein.
  
     0.560
PAE2503
Conserved hypothetical protein, frameshift.
  
     0.552
PAE0172
Conserved hypothetical protein.
  
     0.489
PAE1270
Conserved hypothetical protein.
 
     0.482
PAE0967
Conserved hypothetical protein.
 
     0.473
PAE2695
Hypothetical; Conserved within genome.
 
     0.465
PAE2541a
Hypothetical protein.
       0.434
PAE2544
Conserved hypothetical protein.
       0.434
PAE3499
Conserved hypothetical protein.
  
     0.422
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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