Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
PAE2582Thiosulfate sulfurtransferase; Central intermediary metabolism; Sulfur metabolism. (231 aa)    
Predicted Functional Partners:
PAE2580
Conserved hypothetical protein.
     
 0.795
thiI
Thiamine biosynthesis protein (thiI), probable; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 
 0.692
PAE2366
Glutaredoxin-like protein; Purines, pyrimidines, nucleosides, and nucleotides; 2'-Deoxyribonucleotide metabolism.
    
 0.589
PAE2374
Hypothetical protein.
    
 0.589
PAE2577
Ferredoxin-nitrite reductase; Energy metabolism; Electron transport.
     
 0.570
PAE2578
Conserved hypothetical protein.
       0.559
PAE2575
Phosphoadenosine phosphosulfate reductase (PAPS reductase); Central intermediary metabolism; Sulfur metabolism.
     
 0.513
PAE0727
Molybdenum cofactor biosynthesis protein D/E; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
     
 0.502
PAE1131
Flavoprotein reductase, conjectural; Central intermediary metabolism; Sulfur metabolism.
   
 0.465
PAE1841
Conserved hypothetical protein.
   
 0.465
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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