| node1 | node2 | node1 annotation | node2 annotation | score |
| PAE0585 | PAE0590 | Siroheme synthesis protein, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin. | uroporphyrin-III C-methyltransferase; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin; Belongs to the precorrin methyltransferase family. | 0.993 |
| PAE0585 | PAE1989 | Siroheme synthesis protein, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin. | Conserved hypothetical protein. | 0.579 |
| PAE0585 | PAE2575 | Siroheme synthesis protein, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin. | Phosphoadenosine phosphosulfate reductase (PAPS reductase); Central intermediary metabolism; Sulfur metabolism. | 0.579 |
| PAE0585 | PAE2577 | Siroheme synthesis protein, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin. | Ferredoxin-nitrite reductase; Energy metabolism; Electron transport. | 0.728 |
| PAE0585 | PAE2609 | Siroheme synthesis protein, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin. | Sulfate adenylyltransferase; Central intermediary metabolism; Sulfur metabolism. | 0.719 |
| PAE0590 | PAE0585 | uroporphyrin-III C-methyltransferase; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin; Belongs to the precorrin methyltransferase family. | Siroheme synthesis protein, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin. | 0.993 |
| PAE0590 | PAE1989 | uroporphyrin-III C-methyltransferase; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin; Belongs to the precorrin methyltransferase family. | Conserved hypothetical protein. | 0.658 |
| PAE0590 | PAE2575 | uroporphyrin-III C-methyltransferase; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin; Belongs to the precorrin methyltransferase family. | Phosphoadenosine phosphosulfate reductase (PAPS reductase); Central intermediary metabolism; Sulfur metabolism. | 0.708 |
| PAE0590 | PAE2577 | uroporphyrin-III C-methyltransferase; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin; Belongs to the precorrin methyltransferase family. | Ferredoxin-nitrite reductase; Energy metabolism; Electron transport. | 0.896 |
| PAE0590 | PAE2609 | uroporphyrin-III C-methyltransferase; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin; Belongs to the precorrin methyltransferase family. | Sulfate adenylyltransferase; Central intermediary metabolism; Sulfur metabolism. | 0.701 |
| PAE1989 | PAE0585 | Conserved hypothetical protein. | Siroheme synthesis protein, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin. | 0.579 |
| PAE1989 | PAE0590 | Conserved hypothetical protein. | uroporphyrin-III C-methyltransferase; Biosynthesis of cofactors, prosthetic groups, and carriers; Heme, porphyrin and cobalamin; Belongs to the precorrin methyltransferase family. | 0.658 |
| PAE1989 | PAE2561 | Conserved hypothetical protein. | Adenylylsulfate reductase beta subunit part 1, authentic frameshift; Central intermediary metabolism; Sulfur metabolism. | 0.901 |
| PAE1989 | PAE2562 | Conserved hypothetical protein. | Adenylylsulfate reductase beta subunit part 2, authentic frameshift; Central intermediary metabolism; Sulfur metabolism. | 0.901 |
| PAE1989 | PAE2563 | Conserved hypothetical protein. | Adenylylsulfate reductase alpha subunit part 1, authentic frameshift; Central intermediary metabolism; Sulfur metabolism. | 0.918 |
| PAE1989 | PAE2564 | Conserved hypothetical protein. | Adenylylsulfate reductase alpha subunit part 2, authentic frameshift; Central intermediary metabolism; Sulfur metabolism. | 0.918 |
| PAE1989 | PAE2575 | Conserved hypothetical protein. | Phosphoadenosine phosphosulfate reductase (PAPS reductase); Central intermediary metabolism; Sulfur metabolism. | 0.921 |
| PAE1989 | PAE2577 | Conserved hypothetical protein. | Ferredoxin-nitrite reductase; Energy metabolism; Electron transport. | 0.883 |
| PAE1989 | PAE2609 | Conserved hypothetical protein. | Sulfate adenylyltransferase; Central intermediary metabolism; Sulfur metabolism. | 0.856 |
| PAE2561 | PAE1989 | Adenylylsulfate reductase beta subunit part 1, authentic frameshift; Central intermediary metabolism; Sulfur metabolism. | Conserved hypothetical protein. | 0.901 |