Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE2618Flavoprotein reductase, conjectural; Energy metabolism; Electron transport. (380 aa)    
Predicted Functional Partners:
PAE2834
Conserved hypothetical protein.
 
  
 
0.927
PAE2614
Nitrate reductase gamma subunit (narI); Energy metabolism; Electron transport.
    
  0.924
PAE2420
Cystathionine gamma-synthase; Amino acid biosynthesis; Aspartate family.
  
 
 0.919
PAE1331
Conserved iron-sulfur protein; Unclassified.
  
 
 0.910
PAE2371
NADH oxidase (nox); Cellular processes; Toxin production and resistance.
    
  0.903
PAE2571
Sulfite reductase beta subunit; Central intermediary metabolism; Sulfur metabolism.
    
  0.903
PAE2572
Sulfite reductase alpha subunit; Central intermediary metabolism; Sulfur metabolism.
    
  0.903
PAE2596
Sulfite reductase alpha subunit; Central intermediary metabolism; Sulfur metabolism.
    
  0.903
PAE2597
Sulfite reductase beta subunit; Central intermediary metabolism; Sulfur metabolism.
    
  0.903
PAE2730
Selenium binding protein, probable; Transport and binding proteins; Other.
     
  0.900
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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