STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE2649Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase); Energy metabolism; Glycolysis/gluconeogenesis. (452 aa)    
Predicted Functional Partners:
PAE2644
Pyruvate dehydrogenase E1 alpha subunit; Energy metabolism; Glycolysis/gluconeogenesis.
 
 
 0.999
PAE2646
Pyruvate dehydrogenase E1 beta subunit; Energy metabolism; Glycolysis/gluconeogenesis.
 
 0.999
PAE2648
Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase); Energy metabolism; Glycolysis/gluconeogenesis.
 0.999
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 0.946
PAE0938
2-oxoacid ferredoxin oxidoreductase beta subunit; Energy metabolism; Electron transport.
    
 0.912
PAE0939
2-oxoacid ferredoxin oxidoreductase alpha subunit; Energy metabolism; Electron transport.
  
 
 0.912
PAE1558
2-oxoacid ferredoxin oxidoreductase beta subunit; Energy metabolism; Electron transport.
    
 0.912
PAE1559
2-oxoacid ferredoxin oxidoreductase alpha subunit; Energy metabolism; Electron transport.
  
 
 0.912
PAE2736
2-oxoacid ferredoxin oxidoreductase alpha subunit; Energy metabolism; Electron transport.
  
 
 0.912
PAE2737
2-oxoacid ferredoxin oxidoreductase beta subunit; Energy metabolism; Electron transport.
    
 0.912
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.