STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE2690Iron-sulfur protein, putative; Energy metabolism; Electron transport. (154 aa)    
Predicted Functional Partners:
PAE0716
Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle.
 
 0.989
PAE0718
Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle.
  
 0.989
PAE2563
Adenylylsulfate reductase alpha subunit part 1, authentic frameshift; Central intermediary metabolism; Sulfur metabolism.
  
 0.958
PAE2564
Adenylylsulfate reductase alpha subunit part 2, authentic frameshift; Central intermediary metabolism; Sulfur metabolism.
  
 0.958
PAE0719
Succinate dehydrogenase subunit D (sdhD); Energy metabolism; TCA cycle.
  
 
 0.947
PAE1349
Rieske iron sulfur protein (parR); Energy metabolism; Electron transport.
  
 
 0.899
PAE1580
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
  
 
 0.896
PAE2926
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
  
 
 0.870
sucD
succinyl-CoA synthetase alpha subunit (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.832
PAE1499
Aconitate hydratase; Energy metabolism; TCA cycle.
  
 
 0.815
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.