STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE2777Hypothetical protein. (106 aa)    
Predicted Functional Partners:
PAE2459
Anthranilate synthase component II; Amino acid biosynthesis; Aromatic amino acid family.
  
 
 0.966
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
 
 0.965
trpC
Indole-3-glycerol-phosphate synthase; Amino acid biosynthesis; Aromatic amino acid family; Belongs to the TrpC family.
  
 
 0.962
trpF
Phosphoribosyl anthranilate isomerase; Amino acid biosynthesis; Aromatic amino acid family; Belongs to the TrpF family.
  
  
 0.856
PAE2458
Tryptophan synthase alpha subunit; Amino acid biosynthesis; Aromatic amino acid family.
  
  
 0.776
PAE2778
Type II secretion system protein, conjectural; Protein fate; Protein and peptide secretion and trafficking.
  
    0.776
PAE2779
Hypothetical protein.
       0.773
PAE2780
P. aerophilum family 453; Hypothetical; Conserved within genome.
       0.580
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
     
 0.577
PAE2775
Hypothetical protein.
       0.522
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.