Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PAE2778Type II secretion system protein, conjectural; Protein fate; Protein and peptide secretion and trafficking. (289 aa)    
Predicted Functional Partners:
PAE2779
Hypothetical protein.
  
  
 0.965
PAE0772
Hypothetical protein.
  
  
 0.884
PAE2777
Hypothetical protein.
  
    0.775
PAE2399
Type II secretion system protein, conjectural; Protein fate; Protein and peptide secretion and trafficking.
  
     0.664
PAE3216
Conserved hypothetical protein.
  
   
 0.657
PAE2780
P. aerophilum family 453; Hypothetical; Conserved within genome.
       0.594
PAE1599
Hypothetical protein.
     
 0.557
trmY
Hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
   
    0.547
PAE2775
Hypothetical protein.
       0.522
pcm
protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
       0.470
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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