Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE2785ABC transporter ATP-binding protein, putative; Transport and binding proteins; Unknown substrate. (221 aa)    
Predicted Functional Partners:
PAE3663
Conserved hypothetical protein.
 
 
 0.845
PAE3684
Conserved hypothetical protein.
 
 
 0.845
PAE2288
Conserved hypothetical protein.
 
 
 0.843
PAE0039
Conserved hypothetical protein.
 
 
 0.835
PAE3665
Conserved hypothetical protein.
       0.592
PAE2786
paREP5ab, internal deletion and authentic frameshift; Hypothetical; Conserved within genome.
       0.551
hisS
histidyl-tRNA synthetase; Protein synthesis; tRNA aminoacylation; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
   
 0.506
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
 
   
 0.500
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family.
 
     0.497
rpl14
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
 
     0.494
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.