node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PAE0835 | PAE1027 | PAE0835 | PAE1027 | Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family. | Ribose 5-phosphate isomerase; Energy metabolism; Pentose phosphate pathway. | 0.928 |
PAE0835 | PAE1927 | PAE0835 | PAE1927 | Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family. | Transketolase (C terminal section); Energy metabolism; Pentose phosphate pathway. | 0.921 |
PAE0835 | PAE1929 | PAE0835 | PAE1929 | Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family. | Transketolase (N terminal section); Energy metabolism; Pentose phosphate pathway. | 0.920 |
PAE0835 | guaA | PAE0835 | PAE3369 | Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.692 |
PAE0835 | pdxS | PAE0835 | PAE2819 | Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family. | Stress induced protein, conjectural; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.839 |
PAE0835 | pdxT | PAE0835 | PAE2820 | Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family. | Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.836 |
PAE0835 | prs | PAE0835 | PAE2980 | Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.946 |
PAE0835 | purA | PAE0835 | PAE0974 | Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family. | Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.652 |
PAE1027 | PAE0835 | PAE1027 | PAE0835 | Ribose 5-phosphate isomerase; Energy metabolism; Pentose phosphate pathway. | Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family. | 0.928 |
PAE1027 | PAE1927 | PAE1027 | PAE1927 | Ribose 5-phosphate isomerase; Energy metabolism; Pentose phosphate pathway. | Transketolase (C terminal section); Energy metabolism; Pentose phosphate pathway. | 0.920 |
PAE1027 | PAE1929 | PAE1027 | PAE1929 | Ribose 5-phosphate isomerase; Energy metabolism; Pentose phosphate pathway. | Transketolase (N terminal section); Energy metabolism; Pentose phosphate pathway. | 0.920 |
PAE1027 | guaA | PAE1027 | PAE3369 | Ribose 5-phosphate isomerase; Energy metabolism; Pentose phosphate pathway. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.803 |
PAE1027 | pdxS | PAE1027 | PAE2819 | Ribose 5-phosphate isomerase; Energy metabolism; Pentose phosphate pathway. | Stress induced protein, conjectural; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.803 |
PAE1027 | pdxT | PAE1027 | PAE2820 | Ribose 5-phosphate isomerase; Energy metabolism; Pentose phosphate pathway. | Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.802 |
PAE1027 | prs | PAE1027 | PAE2980 | Ribose 5-phosphate isomerase; Energy metabolism; Pentose phosphate pathway. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.948 |
PAE1027 | purA | PAE1027 | PAE0974 | Ribose 5-phosphate isomerase; Energy metabolism; Pentose phosphate pathway. | Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.445 |
PAE1927 | PAE0835 | PAE1927 | PAE0835 | Transketolase (C terminal section); Energy metabolism; Pentose phosphate pathway. | Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family. | 0.921 |
PAE1927 | PAE1027 | PAE1927 | PAE1027 | Transketolase (C terminal section); Energy metabolism; Pentose phosphate pathway. | Ribose 5-phosphate isomerase; Energy metabolism; Pentose phosphate pathway. | 0.920 |
PAE1927 | PAE1929 | PAE1927 | PAE1929 | Transketolase (C terminal section); Energy metabolism; Pentose phosphate pathway. | Transketolase (N terminal section); Energy metabolism; Pentose phosphate pathway. | 0.999 |
PAE1927 | pdxS | PAE1927 | PAE2819 | Transketolase (C terminal section); Energy metabolism; Pentose phosphate pathway. | Stress induced protein, conjectural; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.817 |