STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysZAcetylglutamate kinase (argB); Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (261 aa)    
Predicted Functional Partners:
lysY
N-acetyl-gamma-glutamyl-phosphate reductase (argC); Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
 
 0.999
argG
Argininosuccinate synthase (argG); Amino acid biosynthesis; Glutamate family; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
  
 0.994
argH
Argininosuccinate lyase (argH); Amino acid biosynthesis; Glutamate family.
 
  
 0.994
lysJ
Acetylornithine aminotransferase (argD); Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
 
  
 0.993
PAE1240
Protein synthesis; Ribosomal proteins: synthesis and modification.
    
 0.924
argF
Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.899
carB
Carbamoyl-phosphate synthase large subunit; Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis.
  
  
 0.855
carA
Carbamoyl-phosphate synthase small subunit; Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis; Belongs to the CarA family.
  
  
 0.830
PAE2879
Hypothetical protein.
       0.794
PAE2883
Hypothetical protein.
     
 0.766
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.