STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
taw3Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (216 aa)    
Predicted Functional Partners:
dapAL
Dihydrodipicolinate synthase; Amino acid biosynthesis; Aspartate family; Belongs to the DapA family.
 
     0.786
PAE2911
P. aerophilum family 453, possible regulatory protein; Regulatory functions; General.
       0.686
PAE1486
Conserved hypothetical protein.
 
  
 0.666
taw1
Conserved hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
  
  
 0.642
PAE3561
Conserved hypothetical protein.
   
    0.641
PAE0841
Conserved hypothetical protein.
  
     0.540
PAE2916
Hypothetical protein.
       0.522
PAE2224
Conserved hypothetical protein.
  
     0.521
PAE2242
Conserved hypothetical protein.
  
     0.508
PAE2918
tldD, putative modulator of DNA gyrase; DNA metabolism; DNA replication, recombination, and repair.
       0.480
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.