Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dapALDihydrodipicolinate synthase; Amino acid biosynthesis; Aspartate family; Belongs to the DapA family. (301 aa)    
Predicted Functional Partners:
PAE2876
Aspartate-semialdehyde dehydrogenase (asd); Amino acid biosynthesis; Aspartate family.
 
 
 0.973
PAE2868
Homoserine dehydrogenase; Amino acid biosynthesis; Aspartate family.
  
 
 0.941
rps17e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eS17 family.
  
    0.912
PAE3044
Conserved hypothetical protein; Belongs to the PDCD5 family.
 
    0.834
rps15
Protein synthesis; Ribosomal proteins: synthesis and modification.
  
    0.822
cmk
Cytidylate kinase (cmk); Purines, pyrimidines, nucleosides, and nucleotides; Nucleotide and nucleoside interconversions.
  
    0.806
PAE2877
Aspartate kinase; Amino acid biosynthesis; Aspartate family.
 
  
 0.797
rpl22
Ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
    0.785
taw3
Conserved hypothetical protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family.
 
     0.785
rpl14e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eL14 family.
   
    0.776
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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