STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppSConserved hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (238 aa)    
Predicted Functional Partners:
PAE1013
Polyprenyl synthetase; Unclassified; Belongs to the FPP/GGPP synthase family.
 
 
 0.967
PAE1702
Conserved hypothetical protein.
 
  
 0.874
pyrH
Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.865
PAE2942a
methionyl-tRNA synthetase beta subunit; Protein synthesis; tRNA aminoacylation.
     
 0.843
PAE2941
Conserved hypothetical protein.
       0.793
pyrG
CTP synthase (pyrG); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.759
metG
methionyl-tRNA synthetase alpha subunit; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
  
    0.758
nusA
Transcription termination factor NusA, putative; Participates in transcription termination. Belongs to the NusA family.
  
    0.713
PAE0705
Conserved hypothetical protein.
  
    0.713
PAE3215
Conserved hypothetical protein.
   
    0.687
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.