STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE2947Conserved hypothetical protein. (250 aa)    
Predicted Functional Partners:
PAE0969
Molybdenum cofactor biosynthesis protein (moaB); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
     
 0.622
PAE2946
Hypothetical protein.
       0.599
PAE2945
Hypothetical protein.
       0.596
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
  
    0.565
PAE3301
mutT/nudix family protein; DNA metabolism; DNA replication, recombination, and repair.
 
 
 0.550
PAE2479
enoyl-CoA hydratase; Fatty acid and phospholipid metabolism; Degradation.
 
 
 0.546
PAE1543
Conserved hypothetical protein.
 
 
 0.523
PAE2253
mutT/nudix family protein; DNA metabolism; DNA replication, recombination, and repair.
 
 
 0.518
fni
Conserved protein (possible oxidoreductase); Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
  0.508
PAE2795
Serine protease; Protein fate; Degradation of proteins, peptides, and glycopeptides.
  
 
  0.507
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.