STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE2983Conserved hypothetical protein. (209 aa)    
Predicted Functional Partners:
PAE2985
Riboflavin specific deaminase, putative; Biosynthesis of cofactors, prosthetic groups, and carriers; Riboflavin, FMN, and FAD.
     
 0.748
gch3
Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
 
   
 0.744
PAE0419
Glycosyl transferase, putative; Unclassified.
  
  
 0.728
PAE1584
Hypothetical; Conserved within genome.
  
  
 0.728
PAE1839
Glycosyl transferase, putative; Unclassified.
  
  
 0.728
PAE2355
Glycosyl transferase; Unclassified.
  
  
 0.728
PAE2986
GTP cyclohydrolase II; Biosynthesis of cofactors, prosthetic groups, and carriers; Riboflavin, FMN, and FAD.
       0.607
PAE3155
Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
       0.545
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
    0.538
fni
Conserved protein (possible oxidoreductase); Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
  
 0.516
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.