STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE3024Sugar-phosphate nucleotidyl transferase; Energy metabolism; Biosynthesis and degradation of polysaccharides. (363 aa)    
Predicted Functional Partners:
eif2a
Translation initiation factor aIF-2 alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
  
 0.886
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
   
 0.885
PAE1244
Translation initiation factor aIF-2B subunit, conjectural; Protein synthesis; Translation factors.
   
 0.877
PAE0064
Translation initiation factor aIF-2 gamma subunit, putative; Protein synthesis; Translation factors.
   
 0.798
PAE1764
GTP-binding protein; Unclassified.
   
 0.798
PAE2053
Pleiotropic regulatory protein, conjectural; Regulatory functions; General; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.685
PAE1922
UDP-glucose 4-epimerase (galE-1); Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
 
 0.673
PAE3631
NAD dependent epimerase/dehydratase, putative; Purines, pyrimidines, nucleosides, and nucleotides; Sugar-nucleotide biosynthesis and conversions.
 
 
 0.658
PAE3027
Conserved hypothetical protein.
       0.608
PAE0764
Phosphomannomutase (pmm); Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides; Belongs to the phosphohexose mutase family.
  
  
 0.530
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.