Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE3246Conserved hypothetical protein. (175 aa)    
Predicted Functional Partners:
PAE3247
Morphine 6-dehydrogenase, conjectural; Unclassified.
  
    0.793
PAE3249
Conserved hypothetical protein.
     
 0.718
PAE3250
Conserved hypothetical protein.
     
 0.718
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
       0.652
PAE3245
Hypothetical; Conserved within genome.
       0.645
PAE2464
ABC transporter ATP-binding component; Transport and binding proteins; Amino acids, peptides and amines.
       0.565
PAE3251
Hypothetical protein.
       0.499
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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