STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE3333Conserved hypothetical protein. (249 aa)    
Predicted Functional Partners:
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
  
 0.976
PAE2004
Serine/threonine specific protein phosphatase; Regulatory functions; General.
  
 0.928
PAE0692
Hypothetical protein with partial (eukaryotic) protein kinase domain; Unclassified.
  
 0.927
PAE0815
Serine/threonine protein kinase, putative; Regulatory functions; General.
  
 0.927
PAE0662
Conserved hypothetical protein.
   
 0.857
PAE1226
DNA endonuclease, conjectural; DNA metabolism; DNA replication, recombination, and repair.
  
 0.857
atpB
H+-transporting ATP synthase subunit B (atpB); Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
   
 0.843
srp19
Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
     
 0.839
rpl40e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.834
PAE0753
H+-transporting ATP synthase subunit C (atpC); Energy metabolism; ATP-proton motive force interconversion.
   
 0.833
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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