Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE3333Conserved hypothetical protein. (249 aa)    
Predicted Functional Partners:
PAE2004
Serine/threonine specific protein phosphatase; Regulatory functions; General.
  
 0.954
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
  
 0.943
srp19
Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
       0.919
rps8e
Protein synthesis; Ribosomal proteins: synthesis and modification.
       0.912
PAE0692
Hypothetical protein with partial (eukaryotic) protein kinase domain; Unclassified.
   
 0.894
PAE0815
Serine/threonine protein kinase, putative; Regulatory functions; General.
   
 0.894
PAE1226
DNA endonuclease, conjectural; DNA metabolism; DNA replication, recombination, and repair.
   
 0.887
PAE1536
Conserved protein (possible dual specificity phosphatase); Unclassified.
   
 0.864
rpl44e
Ribosomal protein L44; Binds to the 23S rRNA.
 
 
 0.854
PAE0665
DNA-directed RNA polymerase subunit B (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.847
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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