STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE3404Acyl coenzyme A thioester hydrolase; Fatty acid and phospholipid metabolism; Other. (313 aa)    
Predicted Functional Partners:
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
    0.679
PAE1329
Conserved hypothetical protein; Belongs to the thioesterase PaaI family.
  
 
 0.620
PAE3406
Conserved hypothetical protein.
       0.561
PAE2464
ABC transporter ATP-binding component; Transport and binding proteins; Amino acids, peptides and amines.
 
 
 0.522
PAE2687
Alcohol dehydrogenase (Zinc); Energy metabolism; Fermentation.
 
   
 0.445
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
  
 0.438
PAE1650
enoyl-CoA hydratase, probable; Fatty acid and phospholipid metabolism; Degradation.
 
 
 0.426
PAE1226
DNA endonuclease, conjectural; DNA metabolism; DNA replication, recombination, and repair.
 
   
 0.424
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 
 0.414
PAE2469
Conserved hypothetical protein.
  
  
 0.409
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.