Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE3452Hypothetical; Conserved within genome. (69 aa)    
Predicted Functional Partners:
PAE3449a
Hypothetical protein.
       0.650
PAE3453
Molybdopterin-guanine dinucleotide biosynthesis protein A; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
       0.587
PAE3447
Aminotransferase, class-V; Unclassified.
       0.431
PAE3454
Pullulanase; Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
       0.429
PAE3450
Hypothetical protein.
       0.423
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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