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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
PAE3453Molybdopterin-guanine dinucleotide biosynthesis protein A; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin. (264 aa)    
Predicted Functional Partners:
PAE3048
Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
 0.954
PAE3466
Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
 0.954
PAE3465
Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
 0.951
PAE1934
Conserved protein; Energy metabolism; Other.
    
 0.919
PAE0727
Molybdenum cofactor biosynthesis protein D/E; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
  
  
 0.885
PAE1759
Molybdopterin-guanine dinucleotide biosynthesis protein B, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
  
 
 0.855
PAE3454
Pullulanase; Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
     0.633
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
  
 0.629
PAE0938
2-oxoacid ferredoxin oxidoreductase beta subunit; Energy metabolism; Electron transport.
  
  
 0.620
PAE1043
Pyruvate ferredoxin oxidoreductase beta subunit (porB); Energy metabolism; Fermentation.
  
  
 0.620
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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