Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE3465Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin. (639 aa)    
Predicted Functional Partners:
PAE0969
Molybdenum cofactor biosynthesis protein (moaB); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
 0.979
PAE3453
Molybdopterin-guanine dinucleotide biosynthesis protein A; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
 0.951
PAE3048
Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
  
 
0.931
PAE0727
Molybdenum cofactor biosynthesis protein D/E; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
  
 0.928
PAE3466
Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
  
 
0.920
PAE1934
Conserved protein; Energy metabolism; Other.
    
  0.909
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
 0.836
PAE3464
Hypothetical protein.
       0.792
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
 0.671
PAE2420
Cystathionine gamma-synthase; Amino acid biosynthesis; Aspartate family.
   
   0.657
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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