Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE3469Transcriptional regulatory protein, AsnC family, putative; Regulatory functions; General. (85 aa)    
Predicted Functional Partners:
PAE3471
Transcriptional regulatory protein, AsnC family, putative; Regulatory functions; General.
   
 
 0.824
PAE3468
Conserved hypothetical protein.
  
    0.800
PAE3470
Hypothetical protein.
       0.707
PAE1625
Conserved hypothetical protein.
 
     0.476
PAE2180
DNA-directed DNA polymerase (B1); DNA metabolism; DNA replication, recombination, and repair.
  
   
 0.459
PAE1632
Conserved hypothetical protein; Belongs to the UPF0201 family.
 
     0.441
tiaS
Conserved hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
 
     0.429
pcn1
Proliferating-cell nuclear antigen homolog (PCNA); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
 
  
 0.404
rps3ae
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eS1 family.
 
     0.401
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.