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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE3477Indolepyruvate ferredoxin oxidoreductase alpha subunit part 2, authentic frameshift; Energy metabolism; Fermentation. (390 aa)    
Predicted Functional Partners:
PAE3478
Indolepyruvate ferredoxin oxidoreductase alpha subunit part 1, authentic frameshift; Energy metabolism; Fermentation.
     0.990
PAE3475
Indolepyruvate ferredoxin oxidoreductase beta subunit; Energy metabolism; Fermentation.
 
 
 0.983
PAE3227
Glutamate synthase small subunit gltD; Amino acid biosynthesis; Glutamate family.
   
 
 0.803
PAE0716
Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle.
  
 
 0.597
PAE2563
Adenylylsulfate reductase alpha subunit part 1, authentic frameshift; Central intermediary metabolism; Sulfur metabolism.
  
 
 0.597
PAE2564
Adenylylsulfate reductase alpha subunit part 2, authentic frameshift; Central intermediary metabolism; Sulfur metabolism.
  
 
 0.597
PAE1040
Pyruvate ferredoxin oxidoreductase gamma subunit (porG); Energy metabolism; Fermentation.
  
 
 0.513
PAE3279
2-ketoacid ferredoxin oxidoreductase gamma subunit; Energy metabolism; Fermentation.
  
 
 0.513
PAE3480
Transcription associated protein, conjectural; Transcription; DNA-dependent RNA polymerase.
       0.503
PAE2609
Sulfate adenylyltransferase; Central intermediary metabolism; Sulfur metabolism.
  
  
 0.455
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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