Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE3495Conserved hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate. (228 aa)    
Predicted Functional Partners:
PAE3068
Phosphoglycolate phosphatase (pgp), conjectural; Energy metabolism; Sugars.
  
 
 0.962
PAE1038
D-3-phosphoglycerate dehydrogenase (serA); Amino acid biosynthesis; Serine family; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.918
PAE1282
Glycolate oxidase subunit glcF; Central intermediary metabolism; Other.
    
  0.905
PAE1284
Glycolate oxidase subunit glcE; Central intermediary metabolism; Other.
    
 0.902
PAE1286
Glycolate oxidase subunit glcD; Central intermediary metabolism; Other.
    
 0.902
PAE2035
D-lactate dehydrogenase; Energy metabolism; Fermentation.
    
 0.902
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
  
    0.681
PAE1610
Glucose-6-phosphate isomerase, conjectural; Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.
  
 
 0.579
argS
arginyl-tRNA synthetase; Protein synthesis; tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
    0.568
PAE0318
Hypothetical protein.
 
  
 0.525
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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