STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spt4DNA-directed RNA polymerase subunit E'' (rpoE2); Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (73 aa)    
Predicted Functional Partners:
spt5
Transcription antitermination protein nusG, putative; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
 
 0.999
PAE3562
DNA-directed RNA polymerase subunit E' (rpoE1); Transcription; DNA-dependent RNA polymerase.
 
 
 0.996
rps27ae
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eS31 family.
  
    0.824
rpoP
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
   
  
 0.704
PAE3561
Conserved hypothetical protein.
       0.692
PAE0666
DNA-directed RNA polymerase subunit A' (rpoA1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.685
rpoA2
DNA-directed RNA polymerase subunit A'' (rpoA2); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.604
PAE3560
Hypothetical protein.
       0.569
PAE3559
HIT family protein; Unclassified.
       0.558
rps6e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eS6 family.
 
    0.537
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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