STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE3573Conserved hypothetical protein. (196 aa)    
Predicted Functional Partners:
PAE3574
Conserved hypothetical protein.
 
     0.700
PAE0264
Signal peptidase; Protein fate; Protein and peptide secretion and trafficking.
  
 
 0.678
PAE1543
Conserved hypothetical protein.
  
     0.649
PAE0879
Conserved hypothetical protein.
  
     0.613
PAE3547
Heat shock protein, htpX homolog, conjectural; Cellular processes; Adaptations to atypical conditions.
 
  
 0.515
PAE1270
Conserved hypothetical protein.
  
     0.503
rpl5
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
       0.484
PAE3631
NAD dependent epimerase/dehydratase, putative; Purines, pyrimidines, nucleosides, and nucleotides; Sugar-nucleotide biosynthesis and conversions.
  
   0.481
PAE2603
Conserved protein with C terminal acylphosphatase domain; Unclassified.
  
     0.479
PAE2839
Molybdopterin oxidoreductase, molybdopterin binding subunit part 2, authentic frameshift; Energy metabolism; Electron transport.
  
     0.472
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.