STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE3582Conserved hypothetical protein; Belongs to the UPF0237 family. (90 aa)    
Predicted Functional Partners:
PAE3581
Conserved hypothetical protein; Belongs to the UPF0210 family.
 
     0.948
PAE2151
Conserved hypothetical protein.
 
     0.763
PAE3580
Conserved hypothetical protein.
       0.705
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
     
 0.577
PAE3584
Citrate synthase part 1, authentic frameshift; Energy metabolism; TCA cycle.
       0.574
PAE3585
Citrate synthase part 2, authentic frameshift; Energy metabolism; TCA cycle.
       0.574
PAE3586
Electron transfer flavoprotein beta subunit (etfB); Energy metabolism; Electron transport.
       0.475
PAE3587
Electron transfer flavoprotein alpha subunit (etfA); Energy metabolism; Electron transport.
       0.475
flpA
Fibrillarin-like pre-rRNA processing protein (flpA); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
     
 0.405
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.