Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE3582Conserved hypothetical protein; Belongs to the UPF0237 family. (90 aa)    
Predicted Functional Partners:
PAE3581
Conserved hypothetical protein; Belongs to the UPF0210 family.
 
     0.948
PAE2151
Conserved hypothetical protein.
 
     0.767
PAE3580
Conserved hypothetical protein.
       0.705
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
       0.660
PAE3584
Citrate synthase part 1, authentic frameshift; Energy metabolism; TCA cycle.
     
 0.574
PAE3585
Citrate synthase part 2, authentic frameshift; Energy metabolism; TCA cycle.
     
 0.574
PAE3586
Electron transfer flavoprotein beta subunit (etfB); Energy metabolism; Electron transport.
       0.474
PAE3587
Electron transfer flavoprotein alpha subunit (etfA); Energy metabolism; Electron transport.
       0.474
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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